Goal · 22 compounds
Sleep & focus
6 of 22 compounds people take for sleep & focus have been through controlled trials in people
0 approved drugs · 6 controlled trials · 6 human pilots · 7 animal only · 3 no data · each counted by its own meter
FDA Approved 2
- Sleep & focus · Nasal sprayOxytocinHormoneA nose spray pitched for mood and bonding. Approved in 1962 for labor; the nasal-spray trials are split.Controlled trialsFDA approvedfor another useChecked Oct 13
- Sleep & focus · PillMethylene BlueMitochondrialBiohackers take drops for brain energy. Its one brain study: a single 280 mg dose, 26 people, in 2016.Human pilotsFDA approvedfor another useBoxed warning: serotonin syndromeChecked Oct 18
Gray Market 16
- Sleep & focus · Nasal spraySelankNootropicRussian nasal drops for anxiety, approved there in 2009. Every trial so far is Russian.Controlled trialsGray marketChecked Oct 13
- Sleep & focus · PillBromantaneSmall moleculeRussian doctors prescribe it for burnout and fatigue. Every trial so far is Russian; WADA banned it in 1997.Controlled trialsGray marketChecked Oct 18
- Sleep & focus · Nasal spraySemaxNootropicA Russian stroke drug that biohackers spray for focus. Its key stroke trial had 30 patients, in 1997.Human pilotsGray marketChecked Oct 13
- Sleep & focus · Daily shotDSIPNeuropeptideInjected before bed for deeper sleep. A 1992 double-blind insomnia trial called it 'not likely' to help.Human pilotsGray marketChecked Oct 13
- Sleep & focus · PillNoopeptNootropicSold in US supplements as a memory booster. 20 years on the Russian market; no placebo trial published.Human pilotsGray marketChecked Oct 5
- Sleep & focus · Daily shotPinealonBioregulatorUsed in Russia after brain injury. Its best study: a 72-patient Russian report in the developers' patent.Human pilotsGray marketChecked Oct 13
- Sleep & focus · PillDihexaNeurotrophicA lab molecule pitched as a memory drug. Human trials: zero.Animal onlyGray marketChecked Oct 11
- Sleep & focusCortagenBioregulatorA synthetic Cortexin, Russia's brain drug. Its best result: rat nerves regrew 27% faster, in one lab.Animal onlyGray marketChecked Oct 18
- Sleep & focus · PillCyclic Glycine-ProlineNootropicA two-amino-acid ring sold in blackcurrant capsules for the brain. Its 126-person trial posted no results.Animal onlyGray marketChecked Oct 5
- Sleep & focusDNSP-11NeurotrophicEleven amino acids copied from a brain growth protein, for Parkinson's. Human trials: zero; monkeys: three.Animal onlyGray marketChecked Oct 5
- Sleep & focus · Daily shotFGLNeurotrophicSold to nootropic buyers as a memory peptide. Its only published human study: a safety test in 24 men.Animal onlyGray marketNeuron loss in healthy young ratsChecked Oct 4
- Sleep & focusP21NeurotrophicNootropic buyers order it for new brain cells. Fifteen papers, one lab, mice only; human trials: zero.Animal onlyGray marketChecked Oct 18
- Sleep & focus · Nasal sprayPE-22-28NootropicPitched as a fast antidepressant, sold as a nasal spray. Human trials: zero; its mood data are one lab’s mice.Animal onlyGray marketChecked Oct 5
- Sleep & focus · Nasal sprayDS5NootropicA vendor-made nasal spray of Dihexa and Semax. Trials of the blend: zero, and the ratios vary by vendor.No dataGray marketChecked Oct 18
- Sleep & focus · Nasal sprayN-Acetyl SelankNootropicA capped Selank, sold for anxiety. Studies of the capped version: zero.No dataGray marketChecked Oct 18
- Sleep & focus · Nasal sprayN-Acetyl SemaxNootropicSold as a longer-lasting Semax. Trials of the capped version: zero; the parent has two Russian stroke trials.No dataGray marketChecked Oct 18
Also taken for this 4
- Muscle & strength · PillMK-677GH secretagogueTaken nightly for growth hormone and sleep. A year-long trial: +1.1 kg lean mass, no strength gain.Controlled trialsGray marketTrial stopped early over heart failureChecked Oct 18
- Injury & recovery · IV dripCerebrolysinNeurotrophicPig-brain extract given for stroke recovery abroad. 90 trials in PubMed; Cochrane found no effect on deaths.Controlled trialsGray marketChecked Oct 11
- Injury & recovery · Daily shotCortexinBioregulatorCattle-brain peptides prescribed in Russia for stroke. Trial deaths: 7 of 208 on it, none of 64 on placebo.Controlled trialsGray marketChecked Oct 5
- Muscle & strength · Daily shotIpamorelinGH secretagogueSold as the polite growth-hormone releaser that spares cortisol. That claim traces to a 1998 study in pigs.Human pilotsGray marketChecked Oct 18
- Legal today
- 2 FDA approved · 0 Compounded Rx · 20 Gray market
- What people actually run
- Flow State Stack (Selank + Semax + Epitalon)