Pair page — what's published on the two together
Crystagen with Pinealon
Given together once: a 2012 Russian study of 20 elite gymnasts, with no placebo and the two never given apart.
The receipt
- Tested together in people
- 1 study, 20 gymnasts (2012)
- Evidence on the combination
- Evidence · Human pilots
Viner et al., 2012
What each does alone
- Immune · PillCrystagenSold in Russia as an immune-support supplement capsule. Placebo-controlled human trials: zero.Evidence · Animal onlyGray marketChecked Oct 5
- Mind & Sleep · Daily shotPinealonUsed in Russia after brain injury. Its best study: a 72-patient Russian report in the developers' patent.Evidence · Human pilotsGray marketChecked Oct 11
Mechanism overlap · reasoning, not evidence
- Crystagen
- Peptide — Khavinson Short-Peptide Bioregulator (Immune)
- Pinealon
- Peptide — Khavinson Brain Tripeptide Bioregulator
Reasoning, not evidence: what each is described to do says nothing about what they do together.
What the studies found
Elite rhythmic gymnasts (Viner et al., 2012)
- What was given — Twenty elite rhythmic gymnasts were split by stratified randomization: 12 took Crystagen and Pinealon capsules, one capsule twice a day with meals for 20 days of each product (the paper does not say whether at the same time or one after the other), and 8 took no capsules, with no placebo.
- What it found — Heart rate during routines did not change. In the recovery period after training it fell from 83.8 to 74.2 beats a minute in morning sessions and from 87.4 to 77.6 in evening ones in the capsule group, and did not change in controls. The paper says the gymnasts had clinical, biochemical and immune tests but reports no results from them.
- Limits — 20 athletes, no placebo and no blinding, and the two products were never given apart.
No placebo-controlled trial has given Crystagen to anyone, and no study has compared the pair with Crystagen alone (searched October 4, 2026).
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Legal Status
Crystagen: Gray market. No FDA ruling — not on any list.
Pinealon: Gray market. No FDA ruling — not on any list.
References
- Viner IA, Terekhina RN, Trofimova SV, Trofimov AV. Assessment and bioregulating correction of reserves of adaptation of gymnasts to physically loadings. Uchenye zapiski universiteta imeni P.F. Lesgafta. 2012;7(89):29-33. DOI: 10.5930/issn.1994-4683.2012.07.89.p29-33. (In Russian.)
Checked 11 Oct 2026 | A literature lookup, not a recommendation to combine anything.