By goal
Hormones & libido — what actually works, by evidence
Of 13 compounds used for hormones and libido, 7 are approved for that use and 3 more have controlled human trials. The other 3 rest on pilot studies or animal data.
Approved drug 7
- Hormones & libidoUpdated Sep 29ClomipheneMen take a women's fertility pill off-label to raise testosterone. Approved since 1967, for women only.Vision changes may be irreversibleEvidence · Approved drugFDA approved
- Hormones & libidoUpdated Sep 29HCGMen on testosterone use it to stay fertile. The standard 500 IU every-other-day dose comes from a 2005 study.Evidence · Approved drugFDA approved
- Hormones & libidoUpdated Sep 29HMGUrine-derived hormones men add to hCG to make sperm. FDA-approved only for women's IVF, 20 days max.Evidence · Approved drugFDA approved
- Hormones & libidoUpdated Sep 29Insulin8 million Americans need it for diabetes; some bodybuilders inject it for size. Misuse can kill.Hypoglycemia can be fatalEvidence · Approved drugFDA approved
- Hormones & libidoUpdated Sep 29PT-141Approved for women's low desire, used mostly off-label by men. The approval trials: 1,247 women, zero men.Evidence · Approved drugFDA approved
- Hormones & libidoUpdated Sep 29TestosteronePrescribed for low testosterone; also the original anabolic steroid. Normal is 300–1,000 ng/dL.Evidence · Approved drugFDA approved
- Hormones & libidoUpdated Sep 29TriptorelinBodybuilders use one shot to 'restart' testosterone. It's approved to shut testosterone off, within 3–4 weeks.Evidence · Approved drugFDA approved
Human trials 3
- Hormones & libidoUpdated Sep 29Enclomiphene CitrateMen's clinics prescribe it to raise testosterone and keep fertility. The FDA turned it down in 2015.Evidence · Human trialsCompounding pharmacy
- Hormones & libidoUpdated Sep 29GonadorelinClinics swap it in for hCG on TRT. It lasts 2–10 minutes in the blood, and studies of that use are thin.Evidence · Human trialsCompounding pharmacy
- Hormones & libidoUpdated Sep 29KisspeptinClinics sell it as a TRT add-on. Its Phase 2 trials, from two hospital groups, never tested that.Evidence · Human trialsResearch only
Human pilots 1
Animal only 2
- Hormones & libidoUpdated Sep 29TestagenUsed in Russia for falling testosterone. The evidence: rodents from one lab, plus small Russian case reports.Evidence · Animal onlyResearch only
- Hormones & libidoUpdated Sep 29ZuclomipheneClomiphene's other half, tested for hot flashes. Its only Phase 2 result is an unpublished interim readout.Evidence · Animal onlyResearch only
No data 0
None.
- Legal today
- 7 FDA-approved · 2 compoundable · 1 not legal yet · 3 research-only
- What people actually run
- None of the six named stacks
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