Goal · 22 compounds
Muscle & strength
10 of 22 compounds people take for muscle & strength have been through controlled trials in people
4 approved drugs · 6 controlled trials · 6 human pilots · 5 animal only · 1 no data · each counted by its own meter
FDA Approved 3
- Muscle & strength · Daily shotTesamorelinGH secretagogueApproved for HIV-related belly fat; clinics use it off-label. Its 412-patient trial cut belly fat 15–18%.Approved drugFDA approvedChecked Oct 18
- Muscle & strength · Daily shotHGHHormoneAnti-aging clinics sell it for body composition. That story began with 12 men in a 1990 study.Approved drugFDA approvedChecked Oct 5
- Muscle & strength · PillMacimorelinGH secretagogueMacrilen: a drink that tests adults for low growth hormone. It missed 19 of 74 the insulin test flagged.Human pilotsFDA approvedfor another useChecked Oct 5
Compounded Rx 1
Gray Market 14
- Muscle & strength · Daily shotGHRP-2GH secretagogueClinic users inject it 2–3 times a day. Its only approval: a one-shot growth-hormone test in Japan, 2004.Controlled trialsGray marketChecked Oct 18
- Muscle & strength · PillMK-677GH secretagogueTaken nightly for growth hormone and sleep. A year-long trial: +1.1 kg lean mass, no strength gain.Controlled trialsGray marketTrial stopped early over heart failureChecked Oct 18
- Muscle & strength · ShotACE-031Myostatin blockerSold to lifters as a muscle-brake blocker. Top dose: lean mass +3.3% in women 45–75; a boys’ trial stopped.Controlled trialsGray marketTrial stopped over nosebleedsChecked Oct 5
- Muscle & strength · PillAnamorelinGH secretagogueJapan’s Adlumiz, a pill for cancer wasting. In 979 lung-cancer patients, lean mass rose; grip strength didn’t.Controlled trialsGray marketLife-threatening heart rhythms in case reportsChecked Oct 5
- Muscle & strength · Weekly shotCJC-1295GH secretagogueAnti-aging clinics pair it with ipamorelin for growth hormone. Human data: 78 people in three Phase 1 trials.Human pilotsGray marketChecked Oct 18
- Muscle & strength · Daily shotIpamorelinGH secretagogueSold as the polite growth-hormone releaser that spares cortisol. That claim traces to a 1998 study in pigs.Human pilotsGray marketChecked Oct 18
- Muscle & strength · Daily shotGHRP-6GH secretagogueThe 1984 original, now taken mostly for its hunger kick. Its GH data in people: short tests, 1 record review.Human pilotsGray marketChecked Oct 13
- Muscle & strength · Daily shotHexarelinGH secretagogueKnown for the biggest growth-hormone pulse of its family. The catch: it fades within 2–4 weeks of daily use.Human pilotsGray marketChecked Oct 18
- Muscle & strengthFollistatin-344Myostatin blockerBodybuilders buy vials to lift the body's muscle brake. Controlled human trials of vial follistatin: zero.Animal onlyGray marketChecked Oct 18
- Muscle & strengthIGF-1 DESIGF-1 variantBodybuilders inject it into a muscle for 'spot growth'. Human studies of it: zero; it lasts 20–30 minutes.Animal onlyGray marketChecked Oct 5
- Muscle & strength · Daily shotIGF-1 LR3IGF-1 variantTaken by advanced lifters for muscle growth. Randomized human trials of this version: zero.Animal onlyGray marketChecked Oct 18
- Muscle & strength · Weekly shotMGFIGF-1 variantLifters inject it into a muscle right after training. Human trials: zero; it lasts 5–7 minutes.Animal onlyGray marketChecked Oct 18
- Muscle & strength · Weekly shotPEG-MGFIGF-1 variantLonger-lasting MGF, taken with BPC-157 or TB-500 by strength crowds. Human trials: zero.Animal onlyGray marketChecked Oct 18
- Muscle & strength · Weekly shotFLGR-242Myostatin blockerA codenamed follistatin, sold by the company its promoter co-founded. Published studies of it: zero.No dataGray marketChecked Oct 18
Also taken for this 4
- Libido & hormones · Daily shotInsulinHormone8 million Americans need it for diabetes; some bodybuilders inject it for size. Misuse can kill.Approved drugFDA approvedHypoglycemia can be fatalChecked Oct 18
- Libido & hormones · Weekly shotTestosteroneHormonePrescribed for low testosterone; also the original anabolic steroid. Normal is 300–1,000 ng/dL.Approved drugFDA approvedChecked Oct 18
- Longevity · Daily shotSS-31MitochondrialApproved in 2025 for a rare mitochondrial disease. Off-label longevity use rests on Phase 2 data.Human pilotsFDA approvedfor another useChecked Oct 18
- Weight loss · IV dripBimagrumabMyostatin blockerPitched as fat loss that keeps muscle. Alone, it took off less weight than semaglutide in a 507-adult trial.Controlled trialsGray marketChecked Oct 5
- Legal today
- 6 FDA approved · 1 Compounded Rx · 15 Gray market