Pair page
Chonluten with Thymagen
Mechanism-tag overlap and published literature for Chonluten and Thymagen, pulled verbatim from each Kalios compound profile. Kalios is a literature reference, not a recommendation.
Mechanism overlap
Mechanism tags are verbatim labels on each compound's profile. Generic tags ("peptide", "small-molecule", "research-chemical") are excluded from this overlap view. Tags are descriptive — not an inference about combined effect.
khavinson-bronchial-mucosal-bioregulator
khavinson-thymic-immune-bioregulator
Co-administration notes from the literature
Verbatim summary text pulled from each compound's profile data. Researchers studying Chonluten and Thymagen have published these mechanism-level observations. Not a co-administration recommendation.
Lung-tissue Khavinson tripeptide (Glu-Asp-Gly). Paired with Thymagen in respiratory-focused immune protocols, particularly in Russian bronchopulmonary practice.
Quick facts
Chonluten
Thymagen
Literature table
Classified references from each compound profile. Click a column header to sort. Click a PMID to open PubMed. Findings are quoted verbatim from each profile's literature_summary; nothing here is added or interpreted.
| Year | Compound | Source | Finding |
|---|---|---|---|
| 2021 | Chonluten | Khavinson VKh, Popovich IG, Linkova NS, Mironova ES, Ilina AR. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22):7053. PMID: 34834147. PMID 34834147 | systematic review |
| 2006 | Chonluten | Gumen AV, Kozinets IA, Shanin SN, Malinin VV, Rybakina EG. Production of lymphocyte-activating factors by mouse macrophages during aging and under the effect of short peptides. Bulletin of Experimental Biology and Medicine. 2006;142(3):360-362. PMID: 17266159. PMID 17266159 | preclinical, in vivo |
| 2016 | Chonluten | Linkova NS, Drobintseva AO, Orlova OA, Kuznetsova EP, Polyakova VO, Kvetnoy IM, Khavinson VKh. Peptide regulation of skin fibroblast functions during their aging in vitro. Bulletin of Experimental Biology and Medicine. 2016;161(1):175-178. PMID: 27259486. PMID 27259486 | preclinical, in vitro |
| 2011 | Chonluten | Fedoreyeva LI, Kireev II, Khavinson VKh, Vanyushin BF. Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and the specific interaction of the peptides with deoxyribooligonucleotides and DNA in vitro. Biochemistry (Moscow). 2011;76(11):1210-1219. PM… PMID 22117548 | preclinical, in vitro |
| 2012 | Chonluten | Khavinson VKh, Solov'ev AIu, Zhilinskii DV. Molecular mechanism of the peptide regulation of gene expression: a review. Advances in Gerontology. 2012;25(3):447-456. PMID: 23289233. PMID 23289233 | mechanism / discovery |
| 2020 | Chonluten | Khavinson V, Linkova N, Diatlova A, Trofimova S. Peptide Regulation of Cell Differentiation. Stem Cell Reviews and Reports. 2020;16(1):118-125. PMID: 31813120. DOI: 10.1007/s12015-019-09938-8. PMID 31813120 | bioregulator literature |
| 2016 | Chonluten | Vanyushin BF, Khavinson VKh. Short Biologically Active Peptides as Epigenetic Modulators of Gene Activity. In: Epigenetics — A Different Way of Looking at Genetics. Springer, 2016. DOI: 10.1007/978-3-319-27186-6_5. | bioregulator literature |
| 2012 | Chonluten | Khavinson VKh, Linkova NS, Polyakova VO, Kheifets OV, Tarnovskaya SI, Kvetnoy IM. Peptides tissue-specifically stimulate cell differentiation during their aging. Bulletin of Experimental Biology and Medicine. 2012;153(1):148-151. PMID: 22808513. PMID 22808513 | bioregulator literature |
| 2010 | Chonluten | Anisimov VN, Khavinson VKh. Peptide bioregulation of aging: results and prospects. Biogerontology. 2010;11(2):139-149. PMID: 19633997. PMID 19633997 | bioregulator literature |
| 2005 | Chonluten | Khavinson VKh, Malinin VV. Gerontological Aspects of Genome Peptide Regulation. Karger Publishers, Basel, 2005. ISBN 3-8055-7903-3. | bioregulator literature |
| 2002 | Chonluten | Khavinson VKh. Peptides and ageing. Neuroendocrinology Letters. 2002;23(Suppl 3):11-144. PMID: 12496732. PMID 12496732 | bioregulator literature |
| 1997 | Chonluten | Morozov VG, Khavinson VKh. Natural and synthetic thymic peptides as therapeutics for immune dysfunction. International Journal of Immunopharmacology. 1997;19(9-10):501-505. PMID: 9637343. PMID 9637343 | bioregulator literature |
| 2021 | Thymagen | Khavinson VK, Linkova NS, Kukanova EO, Bolshakova AV, Gainullina AN. Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19. Stem Cell Rev Rep. 2021. PMID: 33575961. PMID 33575961 | human study |
| 1996 | Thymagen | Zhuk EA, Galenok VA. Timogen v lechenii sakharnogo diabeta I tipa [Thymogen in the treatment of type-1 diabetes mellitus]. Ter Arkh. 1996;68(10):12-14. Russian. PMID: 9026934. PMID 9026934 | human study |
| 2001 | Thymagen | Anisimov VN, Khavinson VKh, Morozov VG. Immunomodulatory synthetic dipeptide L-Glu-L-Trp slows down aging and inhibits spontaneous carcinogenesis in rats. Biogerontology. 2001;2(1):47-55. PMID: 11707921. (Chronic rodent dosing — longevity and anti-carcinogenesis signal.) PMID 11707921 | preclinical, in vivo |
| 1989 | Thymagen | Bespalov VG, Troian DN, Petrov AS, Morozov VG, Khavinson VKh. Ingibiruiushchii effekt timogena na razvitie opukholei pishchevoda i predzheludka, indutsirovannykh etilovym efirom N-nitrozosarkozina u krys [Inhibiting effect of thymogen on the development of tumors of the esophagu… PMID 2759010 | preclinical, in vivo |
| 2022 | Thymagen | Khavinson VK, Linkova NS, Kukanova EO, Bolshakova AV, Gainullina AN, Tendler SM, Morozov VG, Tarnovskaya SI, Vanyushin BF, Shataeva LK, Bakaeva ZV. Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line. Int J Mol Sci. 202… | preclinical, in vitro |
| 2021 | Thymagen | Khavinson VK, Popovich IG, Linkova NS, Mironova ES, Ilina AR. Peptide regulation of cell differentiation, gene expression, and protein synthesis. Bull Exp Biol Med. 2021;170(5):707-711. | mechanism / discovery |
| 2003 | Thymagen | Khavinson VK, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003;135(6):590-592. PMID: 12937678. (Methodological style of Khavinson mechanistic papers.) PMID 12937678 | mechanism / discovery |
| 1997 | Thymagen | Kozlov VA, Khavinson VKh. Natural and synthetic thymic peptides as therapeutics for immune dysfunction. Int Immunopharmacol. 1997;19(9-10):501-505. doi:10.1016/S0192-0561(97)00058-1. (Foundational Western-indexed characterization of Thymalin and Thymogen.) | mechanism / discovery |
| 1997 | Thymagen | Morozov VG, Khavinson VKh. Natural and synthetic thymic peptides: isolation, structure, and biological activity. Int J Immunopharmacol. 1997;19(9-10):501-505. (Original characterization.) | mechanism / discovery |
| 2002 | Thymagen | Khavinson VK. Peptides and Ageing. Neuroendocrinol Lett. 2002;23 Suppl 3:11-144. PMID: 12374906. (Foundational review of the Khavinson peptide bioregulator program.) PMID 12374906 | review |
| 2025 | Thymagen | FDA. Bulk Drug Substances Nominated for Use in Compounding under Section 503A of the Federal Food, Drug, and Cosmetic Act. FDA.gov. Updated 2025–2026 (Thymagen / EW dipeptide / Thymogen not listed). | regulatory / registry |
| 2011 | Thymagen | Khavinson VK, Linkova NS, Trofimov AV, Polyakova VO, Sevostyanova NN, Kvetnoy IM. Morphofunctional fundamentals for peptide regulation of aging. Biogerontology. 2011;12(2):95-106. (Supporting mechanistic framework.) | bioregulator literature |
Related pair pages
More research context
Frequently asked
Have Chonluten and Thymagen been studied together?
Researchers have published mechanistic-level co-administration discussion of Chonluten and Thymagen. No human co-administration trials are catalogued in the Kalios profiles. The pair page lists each compound's classified literature; full citations sit on each individual profile.
What mechanisms do Chonluten and Thymagen share?
Chonluten and Thymagen do not share a specific mechanism tag on their Kalios profiles. They appear on the same pair page because at least one profile lists the other in its co-administration data.
What is the FDA status of Chonluten and Thymagen?
Chonluten: Not approved. Thymagen: Not approved. FDA-status text is pulled verbatim from each compound profile. See /fda-pcac-2026.html for the broader FDA Pharmacy Compounding Advisory Committee context.
Where can I find the full research on Chonluten and Thymagen?
Full citation lists, dosing tables from the literature, reconstitution data, and the FDA / WADA status are on the individual compound profiles: the Chonluten profile and the Thymagen profile. The Kalios Stack Research Tool hub lists every compound covered.
Last updated: April 2026